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Profile of Poisoning in a Tertiary Care Hospital

ABSTRACT:

Aims: The aim of this prospective study was to analyze the rate and characteristics of acute poisoning cases admitted to adult intensive care unit (ICU).We report the socio-demographic, laboratory, and clinical features of cases, mortality rate, and the results of our treatment modalities.

Methods: The study was done in patients admitted with history of poisoning in the department of medicine at Victoria Hospital, Bengaluru from January 2011 to December 2011.This study includes 81 consecutive poisoning Patient who were admitted to ICU care. Detailed history and clinical examination were done in all patients. Ventilator support was given to required patient.

Results: Most of the cases were organophosphorus compound poisoning(n=61, 71.3%). Others had consumed drugs which included analgesics, amitryptilne,decongestants, antihypertensives, benzodiazepines.3 had consumed aluminium phosphide and all 3 of them died. The most common indication for mechanical ventilation was respiratory failure which mainly consisted of OP poisoning.

Conclusion: Pesticides were the major cause of poisoning(80.2%), the reasons being agriculture based economic, poverty and easy availability of highly toxic pesticides.The poisoning related mortality could be decreased by improving ICU condition and appropriate supportive care.

Key words: Organophosphorus, ventilator

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Journal Authors

Srinivasa V 1 , Kavya S.T 2, Madhumathi R 3, Amogh Dudhwewala 4

1 2 3 Assistant Professor, Department of Medicine, BMCRI,Bangalore
4 Post-Graduate Student, Department of Medicine, BMCRI,Bangalore

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